A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10055
Swiss-prot Accession numberQ17192 (Sequence in FASTA format)
DescriptionBombyxin A-1 precursor (BBX-A1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-1 B chain; Bombyxin A-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10271
References1   Iwami M., Kawakami A., Ishizaki H., Takahashi S.Y., Adachi T.,Suzuki Y., Nagasawa H., Suzuki A.; "Cloning of a gene encoding bombyxin, an insulin-like brain secretorypeptide of the silkmoth Bombyx mori with prothoracicotropicactivity."; Dev. Growth Differ. 31:31-37(1989).
2  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-1 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10059
Swiss-prot Accession numberQ566B1 (Sequence in FASTA format)
DescriptionBursicon precursor (Bursicon subunit alpha) (Cuticle-tanning hormone).
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein (By similarity)
Developmental StageN/A
Similarity Contains 1 CTCK (C-terminal cystine knot-like) domain.
Tissue SpecificityN/A
Post translational modification N/A
FunctionFinal heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading
Protein Length160 Amino acids
Molecular weight17901
References1  PubMed abstract 15141943
2  PubMed abstract 15811337
Domain NameN/A
Hormone NameBursicon
Mature Hormone SequenceFPVTGHEVQLPPGTKFFCQECQMTAVIHVLKHRGCKPKAIPSFACIGKCTSYVQVSGSKIWQMERTCNCCQESGEREATVVLFCPDAQNEEKRFRKVSTKAPLQCMCRPCGSIEESSIIPQEVAGYSEEGPLYNHFRKSL
Position of mature hormone in Pre-Hormone protein140 Residues from position (21-160)
ReceptorN/A
Gene ID100049169      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10087
Swiss-prot Accession numberQ17192 (Sequence in FASTA format)
DescriptionBombyxin A-1 precursor (BBX-A1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-1 B chain; Bombyxin A-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10271
References1   Iwami M., Kawakami A., Ishizaki H., Takahashi S.Y., Adachi T.,Suzuki Y., Nagasawa H., Suzuki A.; "Cloning of a gene encoding bombyxin, an insulin-like brain secretorypeptide of the silkmoth Bombyx mori with prothoracicotropicactivity."; Dev. Growth Differ. 31:31-37(1989).
2  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-1 B chain
Mature Hormone SequenceQQPQRVHTYCGRHLARTLADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10088
Swiss-prot Accession numberQ17194 (Sequence in FASTA format)
DescriptionBombyxin B-10 precursor (BBX-B10) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-10 B chain; Bombyxin B-10 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length87 Amino acids
Molecular weight9881
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-10 B chain
Mature Hormone SequenceQEVAHTYCGRHLADTLADLCFGVE
Position of mature hormone in Pre-Hormone protein24 Residues from position (20-43)
ReceptorN/A
Gene ID100169715      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10089
Swiss-prot Accession numberQ17194 (Sequence in FASTA format)
DescriptionBombyxin B-10 precursor (BBX-B10) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-10 B chain; Bombyxin B-10 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length87 Amino acids
Molecular weight9881
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-10 A chain
Mature Hormone SequenceSVVDECCFRPCTLDVLLSYCD
Position of mature hormone in Pre-Hormone protein21 Residues from position (67-87)
ReceptorN/A
Gene ID100169715      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10090
Swiss-prot Accession numberQ17196 (Sequence in FASTA format)
DescriptionBombyxin B-11 precursor (BBX-B11) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-11 B chain; Bombyxin B-11 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length93 Amino acids
Molecular weight10744
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-11 B chain
Mature Hormone SequenceQEVARTYCGRHLANILAYVCFGVE
Position of mature hormone in Pre-Hormone protein24 Residues from position (23-46)
ReceptorN/A
Gene ID100169656      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10093
Swiss-prot Accession numberP26736 (Sequence in FASTA format)
DescriptionBombyxin D-1 precursor (BBX-D1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin D-1 B chain; Bombyxin D-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10106
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin D-1 A chain
Mature Hormone SequenceGIADECCLQPCTNDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (71-90)
ReceptorN/A
Gene ID100169725      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10421
Swiss-prot Accession numberP09971 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone (DH);Alpha-SG neuropeptide (Alpha-SGNP); Beta-SG neuropeptide (Beta-SGNP);Pheromone biosynthesis-activating neuropeptide I (PBAN-I) (BoM-PBAN)(Melanization and reddish coloration hormone I) (MRCH-I); Pheromonebiosynthesis-activating neuropeptide II (PBAN-II); Gamma-SGneuropeptide (Gamma-SGNP)].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySuboesophageal ganglion
Post translational modificationN/A
FunctionDiapause hormone (DH) is responsible for induction of embryonic diapause
Protein Length192 Amino acids
Molecular weight22326
References1  PubMed abstract 1280417
2  PubMed abstract 8475067
3  PubMed abstract 1368584
4  PubMed abstract 2775285
5  PubMed abstract 8512566
6  PubMed abstract 3896851
Domain NameN/A
Hormone NameDiapause hormone
Mature Hormone SequenceTDMKDESDRGAHSERGALWFGPRL
Position of mature hormone in Pre-Hormone protein24 Residues from position (24-47)
ReceptorN/A
Gene ID692749      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10422
Swiss-prot Accession numberP09971 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone (DH);Alpha-SG neuropeptide (Alpha-SGNP); Beta-SG neuropeptide (Beta-SGNP);Pheromone biosynthesis-activating neuropeptide I (PBAN-I) (BoM-PBAN)(Melanization and reddish coloration hormone I) (MRCH-I); Pheromonebiosynthesis-activating neuropeptide II (PBAN-II); Gamma-SGneuropeptide (Gamma-SGNP)].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySuboesophageal ganglion
Post translational modificationN/A
Function The three SGNPS are far less active than DH in inducing diapause eggs. Beta-SGNP expressed higher pban activity than PBAN-I, but alpha- and gamma-SGNP were far less active in pheromonotropic activity
Protein Length192 Amino acids
Molecular weight22326
References1  PubMed abstract 1280417
2  PubMed abstract 8475067
3  PubMed abstract 1368584
4  PubMed abstract 2775285
5  PubMed abstract 8512566
6  PubMed abstract 3896851
Domain NameN/A
Hormone NameAlpha-SG neuropeptide
Mature Hormone SequenceIIFTPKL
Position of mature hormone in Pre-Hormone protein7 Residues from position (97-103)
ReceptorN/A
Gene ID692749      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number10423
Swiss-prot Accession numberP09971 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone (DH);Alpha-SG neuropeptide (Alpha-SGNP); Beta-SG neuropeptide (Beta-SGNP);Pheromone biosynthesis-activating neuropeptide I (PBAN-I) (BoM-PBAN)(Melanization and reddish coloration hormone I) (MRCH-I); Pheromonebiosynthesis-activating neuropeptide II (PBAN-II); Gamma-SGneuropeptide (Gamma-SGNP)].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySuboesophageal ganglion
Post translational modificationN/A
Function The three SGNPS are far less active than DH in inducing diapause eggs. Beta-SGNP expressed higher pban activity than PBAN-I, but alpha- and gamma-SGNP were far less active in pheromonotropic activity
Protein Length192 Amino acids
Molecular weight22326
References1  PubMed abstract 1280417
2  PubMed abstract 8475067
3  PubMed abstract 1368584
4  PubMed abstract 2775285
5  PubMed abstract 8512566
6  PubMed abstract 3896851
Domain NameN/A
Hormone NameBeta-SG neuropeptide
Mature Hormone SequenceSVAKPQTHESLEFIPRL
Position of mature hormone in Pre-Hormone protein17 Residues from position (106-122)
ReceptorN/A
Gene ID692749      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number10424
Swiss-prot Accession numberP09971 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone (DH);Alpha-SG neuropeptide (Alpha-SGNP); Beta-SG neuropeptide (Beta-SGNP);Pheromone biosynthesis-activating neuropeptide I (PBAN-I) (BoM-PBAN)(Melanization and reddish coloration hormone I) (MRCH-I); Pheromonebiosynthesis-activating neuropeptide II (PBAN-II); Gamma-SGneuropeptide (Gamma-SGNP)].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySuboesophageal ganglion
Post translational modificationN/A
Function PBAN is an hormone that controls sex pheromone production in female moths. PBAN also mediates visceral muscle contractile activity (myotropic activity). PBAN is identical to MRCH which is implicated in the formation of both melanin in the cuticle and ommochrome in the epidermis of armyworm species
Protein Length192 Amino acids
Molecular weight22326
References1  PubMed abstract 1280417
2  PubMed abstract 8475067
3  PubMed abstract 1368584
4  PubMed abstract 2775285
5  PubMed abstract 8512566
6  PubMed abstract 3896851
Domain NameN/A
Hormone NamePheromone biosynthesis-activating neuropeptide II
Mature Hormone SequenceRLSEDMPATPADQEMYQPDPEEMESRTRYFSPRL
Position of mature hormone in Pre-Hormone protein34 Residues from position (125-158)
ReceptorN/A
Gene ID692749      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number10425
Swiss-prot Accession numberP09971 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone (DH);Alpha-SG neuropeptide (Alpha-SGNP); Beta-SG neuropeptide (Beta-SGNP);Pheromone biosynthesis-activating neuropeptide I (PBAN-I) (BoM-PBAN)(Melanization and reddish coloration hormone I) (MRCH-I); Pheromonebiosynthesis-activating neuropeptide II (PBAN-II); Gamma-SGneuropeptide (Gamma-SGNP)].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySuboesophageal ganglion
Post translational modificationN/A
Function PBAN is an hormone that controls sex pheromone production in female moths. PBAN also mediates visceral muscle contractile activity (myotropic activity). PBAN is identical to MRCH which is implicated in the formation of both melanin in the cuticle and ommochrome in the epidermis of armyworm species
Protein Length192 Amino acids
Molecular weight22326
References1  PubMed abstract 1280417
2  PubMed abstract 8475067
3  PubMed abstract 1368584
4  PubMed abstract 2775285
5  PubMed abstract 8512566
6  PubMed abstract 3896851
Domain NameN/A
Hormone NamePheromone biosynthesis-activating neuropeptide I
Mature Hormone SequenceLSEDMPATPADQEMYQPDPEEMESRTRYFSPRL
Position of mature hormone in Pre-Hormone protein33 Residues from position (126-158)
ReceptorN/A
Gene ID692749      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number10426
Swiss-prot Accession numberP09971 (Sequence in FASTA format)
DescriptionPBAN-type neuropeptides precursor [Contains: Diapause hormone (DH);Alpha-SG neuropeptide (Alpha-SGNP); Beta-SG neuropeptide (Beta-SGNP);Pheromone biosynthesis-activating neuropeptide I (PBAN-I) (BoM-PBAN)(Melanization and reddish coloration hormone I) (MRCH-I); Pheromonebiosynthesis-activating neuropeptide II (PBAN-II); Gamma-SGneuropeptide (Gamma-SGNP)].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the pyrokinin family.
Tissue SpecificitySuboesophageal ganglion
Post translational modificationN/A
Function The three SGNPS are far less active than DH in inducing diapause eggs. Beta-SGNP expressed higher pban activity than PBAN-I, but alpha- and gamma-SGNP were far less active in pheromonotropic activity
Protein Length192 Amino acids
Molecular weight22326
References1  PubMed abstract 1280417
2  PubMed abstract 8475067
3  PubMed abstract 1368584
4  PubMed abstract 2775285
5  PubMed abstract 8512566
6  PubMed abstract 3896851
Domain NameN/A
Hormone NameGamma-SG neuropeptide
Mature Hormone SequenceTMSFSPRL
Position of mature hormone in Pre-Hormone protein8 Residues from position (161-168)
ReceptorN/A
Gene ID692749      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 14

HMRbase accession number10440
Swiss-prot Accession numberP17219 (Sequence in FASTA format)
DescriptionProthoracicotropic hormone precursor (PTTH) [Contains: P2K; P6K;Prothoracicotropic hormone].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationN/A
Developmental StageN/A
Similarity N/A
Tissue SpecificityPTTH is synthesized by two dorsolateral neurosecretory cells of the Bombyx brain
Post translational modificationN/A
FunctionPeptides P2K and P6K are presumed to be cleaved post-translationally and may play some unknown physiologically or developmentally important functions
Protein Length224 Amino acids
Molecular weight26028
References1  PubMed abstract 2315701
2  PubMed abstract 8125124
3  PubMed abstract 1368675
4  PubMed abstract 8180220
Domain NameN/A
Hormone NameP2K
Mature Hormone SequencePDVGGFMVEDQRTHKSHNYMM
Position of mature hormone in Pre-Hormone protein21 Residues from position (33-53)
ReceptorN/A
Gene ID692767      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number10441
Swiss-prot Accession numberP17219 (Sequence in FASTA format)
DescriptionProthoracicotropic hormone precursor (PTTH) [Contains: P2K; P6K;Prothoracicotropic hormone].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationN/A
Developmental StageN/A
Similarity N/A
Tissue SpecificityPTTH is synthesized by two dorsolateral neurosecretory cells of the Bombyx brain
Post translational modificationN/A
FunctionPeptides P2K and P6K are presumed to be cleaved post-translationally and may play some unknown physiologically or developmentally important functions
Protein Length224 Amino acids
Molecular weight26028
References1  PubMed abstract 2315701
2  PubMed abstract 8125124
3  PubMed abstract 1368675
4  PubMed abstract 8180220
Domain NameN/A
Hormone NameP6K
Mature Hormone SequenceARNDVLGDKENVRPNPYYTEPFDPDTSPEELSALIVDYANMIRNDVILLDNSVETRT
Position of mature hormone in Pre-Hormone protein57 Residues from position (56-112)
ReceptorN/A
Gene ID692767      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number10442
Swiss-prot Accession numberP17219 (Sequence in FASTA format)
DescriptionProthoracicotropic hormone precursor (PTTH) [Contains: P2K; P6K;Prothoracicotropic hormone].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationN/A
Developmental StageN/A
Similarity N/A
Tissue SpecificityPTTH is synthesized by two dorsolateral neurosecretory cells of the Bombyx brain
Post translational modificationN/A
FunctionPTTH is a brain secretory polypeptide of insects which stimulates the prothoracic glands to produce and release ecdysone, the steroid essential to insect development
Protein Length224 Amino acids
Molecular weight26028
References1  PubMed abstract 2315701
2  PubMed abstract 8125124
3  PubMed abstract 1368675
4  PubMed abstract 8180220
Domain NameN/A
Hormone NameProthoracicotropic hormone
Mature Hormone SequenceGNIQVENQAIPDPPCTCKYKKEIEDLGENSVPRFIETRNCNKTQQPTCRPPYICKESLYSITILKRRETKSQESLEIPNELKYRWVAESHPVSVACLCTRDYQLRYNNN
Position of mature hormone in Pre-Hormone protein109 Residues from position (116-224)
ReceptorN/A
Gene ID692767      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 17

HMRbase accession number10451
Swiss-prot Accession numberP29519 (Sequence in FASTA format)
DescriptionBombyxin B-12 precursor (BBX-B12) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-12 B chain; Bombyxin B-12 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10124
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-12 B chain
Mature Hormone SequenceEEQEVARTYCGAHLANTLADLCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (21-46)
ReceptorN/A
Gene ID100169722      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 18

HMRbase accession number10527
Swiss-prot Accession numberP15411 (Sequence in FASTA format)
DescriptionBombyxin A-2 precursor (BBX-A2) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-2 B chain; Bombyxin A-2 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight9979
References1  PubMed abstract 2708384
2  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin A-2 B chain
Mature Hormone SequenceQQPQEVHTYCGRHLARTMADLCWEEGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene ID693012      
PDB ID1BOM   1BON      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 19

HMRbase accession number10528
Swiss-prot Accession numberP15411 (Sequence in FASTA format)
DescriptionBombyxin A-2 precursor (BBX-A2) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-2 B chain; Bombyxin A-2 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight9979
References1  PubMed abstract 2708384
2  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin A-2 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (70-89)
ReceptorN/A
Gene ID693012      
PDB ID1BOM   1BON      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 20

HMRbase accession number10529
Swiss-prot Accession numberP26726 (Sequence in FASTA format)
DescriptionBombyxin A-3 precursor (BBX-A3) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-3 B chain; Bombyxin A-3 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10273
References1  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin A-3 B chain
Mature Hormone SequenceQQPQGVHTYCGRHLARTLANLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 21

HMRbase accession number10530
Swiss-prot Accession numberP26726 (Sequence in FASTA format)
DescriptionBombyxin A-3 precursor (BBX-A3) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-3 B chain; Bombyxin A-3 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10273
References1  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin A-3 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 22

HMRbase accession number10531
Swiss-prot Accession numberP26727 (Sequence in FASTA format)
DescriptionBombyxin A-4 precursor (BBX-A4) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-4 B chain; Bombyxin A-4 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10172
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-4 B chain
Mature Hormone SequenceQQPQGVHTYCGRHLARTLADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene ID100169657      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 23

HMRbase accession number10532
Swiss-prot Accession numberP26727 (Sequence in FASTA format)
DescriptionBombyxin A-4 precursor (BBX-A4) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-4 B chain; Bombyxin A-4 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10172
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-4 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene ID100169657      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 24

HMRbase accession number10533
Swiss-prot Accession numberP26728 (Sequence in FASTA format)
DescriptionBombyxin A-5 precursor (BBX-A5) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-5 B chain; Bombyxin A-5 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10299
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-5 B chain
Mature Hormone SequenceQQPQTVHTYCGHHLARTLADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene ID100169658      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 25

HMRbase accession number10534
Swiss-prot Accession numberP26728 (Sequence in FASTA format)
DescriptionBombyxin A-5 precursor (BBX-A5) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-5 B chain; Bombyxin A-5 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10299
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-5 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene ID100169658      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 26

HMRbase accession number10535
Swiss-prot Accession numberP26729 (Sequence in FASTA format)
DescriptionBombyxin A-6 precursor (BBX-A6) (Bombyxin-II) (4K-prothoracicotropichormone) (4K-PTTH) [Contains: Bombyxin A-6 B chain; Bombyxin A-6 Achain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10186
References1  PubMed abstract 8683595
2  PubMed abstract 16593744
3  PubMed abstract 7473749
Domain NameInsulin  
Hormone NameBombyxin A-6 B chain
Mature Hormone SequenceQQPQAVHTYCGRHLARTLADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene IDN/A
PDB ID1BOM   1BON      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 27

HMRbase accession number10536
Swiss-prot Accession numberP26729 (Sequence in FASTA format)
DescriptionBombyxin A-6 precursor (BBX-A6) (Bombyxin-II) (4K-prothoracicotropichormone) (4K-PTTH) [Contains: Bombyxin A-6 B chain; Bombyxin A-6 Achain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10186
References1  PubMed abstract 8683595
2  PubMed abstract 16593744
3  PubMed abstract 7473749
Domain NameInsulin  
Hormone NameBombyxin A-6 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene IDN/A
PDB ID1BOM   1BON      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 28

HMRbase accession number10537
Swiss-prot Accession numberP26730 (Sequence in FASTA format)
DescriptionBombyxin A-7 precursor (BBX-A7) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-7 B chain; Bombyxin A-7 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10286
References1  PubMed abstract 8683595
2  PubMed abstract 16593744
Domain NameInsulin  
Hormone NameBombyxin A-7 B chain
Mature Hormone SequenceQQPQAVHTYCGRHLARTLADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 29

HMRbase accession number10538
Swiss-prot Accession numberP26730 (Sequence in FASTA format)
DescriptionBombyxin A-7 precursor (BBX-A7) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-7 B chain; Bombyxin A-7 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10286
References1  PubMed abstract 8683595
2  PubMed abstract 16593744
Domain NameInsulin  
Hormone NameBombyxin A-7 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 30

HMRbase accession number10539
Swiss-prot Accession numberP26731 (Sequence in FASTA format)
DescriptionBombyxin A-8 precursor (BBX-A8) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-8 B chain; Bombyxin A-8 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight9951
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-8 B chain
Mature Hormone SequenceQQPQEVHTYCGRHLARTMADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene ID100169709      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 31

HMRbase accession number10540
Swiss-prot Accession numberP26731 (Sequence in FASTA format)
DescriptionBombyxin A-8 precursor (BBX-A8) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-8 B chain; Bombyxin A-8 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight9951
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-8 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene ID100169709      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 32

HMRbase accession number10541
Swiss-prot Accession numberP26732 (Sequence in FASTA format)
DescriptionBombyxin A-9 precursor (BBX-A9) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-9 B chain; Bombyxin A-9 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10288
References1  PubMed abstract 8683595
2  PubMed abstract 16593744
Domain NameInsulin  
Hormone NameBombyxin A-9 B chain
Mature Hormone SequenceQQPQAVHTYCGRHLARTLADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 33

HMRbase accession number10542
Swiss-prot Accession numberP26732 (Sequence in FASTA format)
DescriptionBombyxin A-9 precursor (BBX-A9) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-9 B chain; Bombyxin A-9 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10288
References1  PubMed abstract 8683595
2  PubMed abstract 16593744
Domain NameInsulin  
Hormone NameBombyxin A-9 A chain
Mature Hormone SequenceGIVDECCLRPCSVDVLLSYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (73-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 34

HMRbase accession number10543
Swiss-prot Accession numberQ17196 (Sequence in FASTA format)
DescriptionBombyxin B-11 precursor (BBX-B11) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-11 B chain; Bombyxin B-11 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length93 Amino acids
Molecular weight10744
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-11 A chain
Mature Hormone SequenceGPGVVDECCFRPCKLEVLKSFFFFFCD
Position of mature hormone in Pre-Hormone protein27 Residues from position (67-93)
ReceptorN/A
Gene ID100169656      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 35

HMRbase accession number10544
Swiss-prot Accession numberP29519 (Sequence in FASTA format)
DescriptionBombyxin B-12 precursor (BBX-B12) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-12 B chain; Bombyxin B-12 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10124
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-12 A chain
Mature Hormone SequenceGVVDECCFQPCTLDVLLSYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (70-90)
ReceptorN/A
Gene ID100169722      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 36

HMRbase accession number10545
Swiss-prot Accession numberP26733 (Sequence in FASTA format)
DescriptionBombyxin B-1 precursor (BBX-B1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-1 B chain; Bombyxin B-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight9945
References1  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin B-1 B chain
Mature Hormone SequenceEAQEVARTYCGRHLADTLADLCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (20-45)
ReceptorN/A
Gene ID100169719      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 37

HMRbase accession number10546
Swiss-prot Accession numberP26733 (Sequence in FASTA format)
DescriptionBombyxin B-1 precursor (BBX-B1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-1 B chain; Bombyxin B-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight9945
References1  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin B-1 A chain
Mature Hormone SequenceGVVDECCFRPCTLDVLLSYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (69-89)
ReceptorN/A
Gene ID100169719      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 38

HMRbase accession number10547
Swiss-prot Accession numberP26734 (Sequence in FASTA format)
DescriptionBombyxin B-2 precursor (BBX-B2) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-2 B chain; Bombyxin B-2 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight10039
References1  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin B-2 B chain
Mature Hormone SequenceEAQEVARTYCGRHLADTLADLCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (20-45)
ReceptorN/A
Gene ID100169721      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 39

HMRbase accession number10548
Swiss-prot Accession numberP26734 (Sequence in FASTA format)
DescriptionBombyxin B-2 precursor (BBX-B2) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-2 B chain; Bombyxin B-2 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length89 Amino acids
Molecular weight10039
References1  PubMed abstract 2674935
Domain NameInsulin  
Hormone NameBombyxin B-2 A chain
Mature Hormone SequenceGVVDECCFRPCTLDVLLSYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (69-89)
ReceptorN/A
Gene ID100169721      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 40

HMRbase accession number10549
Swiss-prot Accession numberP26737 (Sequence in FASTA format)
DescriptionBombyxin B-3 precursor (BBX-B3) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-3 B chain; Bombyxin B-3 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10152
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-3 B chain
Mature Hormone SequenceEEQEVARTYCGAHLANTLADLCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (21-46)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 41

HMRbase accession number10550
Swiss-prot Accession numberP26737 (Sequence in FASTA format)
DescriptionBombyxin B-3 precursor (BBX-B3) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-3 B chain; Bombyxin B-3 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10152
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-3 A chain
Mature Hormone SequenceGVVDECCFRPCTLDVLLSYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (70-90)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 42

HMRbase accession number10551
Swiss-prot Accession numberP26738 (Sequence in FASTA format)
DescriptionBombyxin B-4 precursor (BBX-B4) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-4 B chain; Bombyxin B-4 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10103
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-4 B chain
Mature Hormone SequenceEAQEVARTYCGRHLADTLADLCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (21-46)
ReceptorN/A
Gene ID100169720      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 43

HMRbase accession number10552
Swiss-prot Accession numberP26738 (Sequence in FASTA format)
DescriptionBombyxin B-4 precursor (BBX-B4) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-4 B chain; Bombyxin B-4 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10103
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-4 A chain
Mature Hormone SequenceGVVDECCFRPCTLDVLLSYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (70-90)
ReceptorN/A
Gene ID100169720      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 44

HMRbase accession number10553
Swiss-prot Accession numberP26739 (Sequence in FASTA format)
DescriptionBombyxin B-5 precursor (BBX-B5) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-5 B chain; Bombyxin B-5 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10212
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-5 B chain
Mature Hormone SequenceEEQEVARTYCGRHLANILAYVCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (21-46)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 45

HMRbase accession number10554
Swiss-prot Accession numberP26739 (Sequence in FASTA format)
DescriptionBombyxin B-5 precursor (BBX-B5) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-5 B chain; Bombyxin B-5 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10212
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-5 A chain
Mature Hormone SequenceGPGVVDECCFRPCKLEVLKSYCGV
Position of mature hormone in Pre-Hormone protein24 Residues from position (67-90)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 46

HMRbase accession number10555
Swiss-prot Accession numberP26740 (Sequence in FASTA format)
DescriptionBombyxin B-6 precursor (BBX-B6) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-6 B chain; Bombyxin B-6 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10112
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-6 B chain
Mature Hormone SequenceEAQEVARTYCGRDLADTLADLCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (21-46)
ReceptorN/A
Gene ID100169723      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 47

HMRbase accession number10556
Swiss-prot Accession numberP26740 (Sequence in FASTA format)
DescriptionBombyxin B-6 precursor (BBX-B6) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-6 B chain; Bombyxin B-6 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10112
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-6 A chain
Mature Hormone SequenceGVVDECCFRPCTLDVLLSYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (70-90)
ReceptorN/A
Gene ID100169723      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 48

HMRbase accession number10557
Swiss-prot Accession numberP26741 (Sequence in FASTA format)
DescriptionBombyxin B-7 precursor (BBX-B7) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-7 B chain; Bombyxin B-7 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10028
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-7 B chain
Mature Hormone SequenceEAQEVARTYCGRHLADTLADLCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (21-46)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 49

HMRbase accession number10558
Swiss-prot Accession numberP26741 (Sequence in FASTA format)
DescriptionBombyxin B-7 precursor (BBX-B7) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-7 B chain; Bombyxin B-7 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10028
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-7 A chain
Mature Hormone SequenceGVVDECCFRPCTLDVLLSYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (70-90)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 50

HMRbase accession number10559
Swiss-prot Accession numberP26742 (Sequence in FASTA format)
DescriptionBombyxin B-8 precursor (BBX-B8) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-8 B chain; Bombyxin B-8 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length88 Amino acids
Molecular weight9706
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-8 B chain
Mature Hormone SequenceEAQEVARTYCGSHLADTLADLCFGVV
Position of mature hormone in Pre-Hormone protein26 Residues from position (19-44)
ReceptorN/A
Gene ID100169718      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 51

HMRbase accession number10560
Swiss-prot Accession numberP26742 (Sequence in FASTA format)
DescriptionBombyxin B-8 precursor (BBX-B8) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-8 B chain; Bombyxin B-8 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length88 Amino acids
Molecular weight9706
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-8 A chain
Mature Hormone SequenceGVVDECCFRPCTLDVLASYCG
Position of mature hormone in Pre-Hormone protein21 Residues from position (68-88)
ReceptorN/A
Gene ID100169718      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 52

HMRbase accession number10561
Swiss-prot Accession numberP26743 (Sequence in FASTA format)
DescriptionBombyxin B-9 precursor (BBX-B9) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-9 B chain; Bombyxin B-9 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10284
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-9 B chain
Mature Hormone SequenceEEQEVARTYCGRHLANILAYVCFGVE
Position of mature hormone in Pre-Hormone protein26 Residues from position (21-46)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 53

HMRbase accession number10562
Swiss-prot Accession numberP26743 (Sequence in FASTA format)
DescriptionBombyxin B-9 precursor (BBX-B9) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin B-9 B chain; Bombyxin B-9 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionBrain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10284
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin B-9 A chain
Mature Hormone SequenceEPGVVDECCFRPCKLEVLKSYCGV
Position of mature hormone in Pre-Hormone protein24 Residues from position (67-90)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 54

HMRbase accession number10563
Swiss-prot Accession numberP15410 (Sequence in FASTA format)
DescriptionBombyxin C-1 precursor (BBX-C1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin C-1 B chain; Bombyxin C-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length91 Amino acids
Molecular weight10137
References1   Iwami M., Adachi T., Kondo H., Kawakami A., Suzuki Y., Nagasawa H.,Suzuki A., Ishizaki H.; "A novel family C of the genes that encode bombyxin, an insulin-related brain secretory peptide of the silkmoth Bombyx mori: isolationand characterization of gene C-1."; Insect Biochem. 20:295-303(1990).
2  PubMed abstract 8683595
3  PubMed abstract 2708384
Domain NameInsulin  
Hormone NameBombyxin C-1 B chain
Mature Hormone SequenceQTASQFYCGDFLARTMSSLCWSDMQ
Position of mature hormone in Pre-Hormone protein25 Residues from position (20-44)
ReceptorN/A
Gene ID100147698      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 55

HMRbase accession number10564
Swiss-prot Accession numberP15410 (Sequence in FASTA format)
DescriptionBombyxin C-1 precursor (BBX-C1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin C-1 B chain; Bombyxin C-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length91 Amino acids
Molecular weight10137
References1   Iwami M., Adachi T., Kondo H., Kawakami A., Suzuki Y., Nagasawa H.,Suzuki A., Ishizaki H.; "A novel family C of the genes that encode bombyxin, an insulin-related brain secretory peptide of the silkmoth Bombyx mori: isolationand characterization of gene C-1."; Insect Biochem. 20:295-303(1990).
2  PubMed abstract 8683595
3  PubMed abstract 2708384
Domain NameInsulin  
Hormone NameBombyxin C-1 A chain
Mature Hormone SequenceGIVDECCYRPCTIDVLMSYCDN
Position of mature hormone in Pre-Hormone protein22 Residues from position (70-91)
ReceptorN/A
Gene ID100147698      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 56

HMRbase accession number10565
Swiss-prot Accession numberP26735 (Sequence in FASTA format)
DescriptionBombyxin C-2 precursor (BBX-C2) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin C-2 B chain; Bombyxin C-2 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length95 Amino acids
Molecular weight10605
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin C-2 B chain
Mature Hormone SequenceQTASQFYCGDFLARTMSILCWPDMP
Position of mature hormone in Pre-Hormone protein25 Residues from position (20-44)
ReceptorN/A
Gene ID100147697      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 57

HMRbase accession number10566
Swiss-prot Accession numberP26735 (Sequence in FASTA format)
DescriptionBombyxin C-2 precursor (BBX-C2) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin C-2 B chain; Bombyxin C-2 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length95 Amino acids
Molecular weight10605
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin C-2 A chain
Mature Hormone SequenceGIVDECCYRPCTTDVLKLYCDKQITI
Position of mature hormone in Pre-Hormone protein26 Residues from position (70-95)
ReceptorN/A
Gene ID100147697      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 58

HMRbase accession number10567
Swiss-prot Accession numberP26736 (Sequence in FASTA format)
DescriptionBombyxin D-1 precursor (BBX-D1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin D-1 B chain; Bombyxin D-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length90 Amino acids
Molecular weight10106
References1  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin D-1 B chain
Mature Hormone SequenceASEEGHIYCGRYLAYKMADLCWRAGFE
Position of mature hormone in Pre-Hormone protein27 Residues from position (19-45)
ReceptorN/A
Gene ID100169725      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 59

HMRbase accession number10568
Swiss-prot Accession numberP21808 (Sequence in FASTA format)
DescriptionBombyxin E-1 precursor (BBX-E1) (Bombyxin IV) (4K-prothoracicotropichormone IV) (4K-PTTH-IV) [Contains: Bombyxin E-1 B chain; Bombyxin E-1A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPTTH is a brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length98 Amino acids
Molecular weight10987
References1  PubMed abstract 9253178
2   Maruyama K., Hietter H., Nagasawa H., Isogai A., Tamura S., Suzuki A.,Ishizaki H.; "Isolation and primary structure of bombyxin-IV, a novel molecularspecies of bombyxin from the silkworm, Bombyx mori."; Agric. Biol. Chem. 52:3035-3041(1988).
3  PubMed abstract 1515030
Domain NameInsulin  
Hormone NameBombyxin E-1 B chain
Mature Hormone SequenceQEANVAHHYCGRHLANTLADLCWDTSVE
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene ID100146109      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 60

HMRbase accession number10569
Swiss-prot Accession numberP21808 (Sequence in FASTA format)
DescriptionBombyxin E-1 precursor (BBX-E1) (Bombyxin IV) (4K-prothoracicotropichormone IV) (4K-PTTH-IV) [Contains: Bombyxin E-1 B chain; Bombyxin E-1A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPTTH is a brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length98 Amino acids
Molecular weight10987
References1  PubMed abstract 9253178
2   Maruyama K., Hietter H., Nagasawa H., Isogai A., Tamura S., Suzuki A.,Ishizaki H.; "Isolation and primary structure of bombyxin-IV, a novel molecularspecies of bombyxin from the silkworm, Bombyx mori."; Agric. Biol. Chem. 52:3035-3041(1988).
3  PubMed abstract 1515030
Domain NameInsulin  
Hormone NameBombyxin E-1 A chain
Mature Hormone SequenceGVVDECCIQPCTLDVLATYC
Position of mature hormone in Pre-Hormone protein20 Residues from position (79-98)
ReceptorN/A
Gene ID100146109      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 61

HMRbase accession number10602
Swiss-prot Accession numberP25331 (Sequence in FASTA format)
DescriptionEclosion hormone precursor (Ecdysis activator) (EH).
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insect eclosion hormone family.
Tissue SpecificityN/A
Post translational modification N/A
Function Neuropeptide that triggers the performance of ecdysis behaviors at the end of a molt. It triggers adult behavior patterns: larval, pupal and adult ecdysis, and plasticization during the molt
Protein Length88 Amino acids
Molecular weight9505
References1  PubMed abstract 1370883
2   Kono T., Nagasawa H., Isogai A., Fugo H., Suzuki A.; "Amino acid sequence of eclosion hormone of the silkworm, Bombyxmori."; Agric. Biol. Chem. 51:2307-2308(1987).
Domain NameEclosion  
Hormone NameEclosion hormone
Mature Hormone SequenceSPAIASSYDAMEICIENCAQCKKMFGPWFEGSLCAESCIKARGKDIPECESFASISPFLNKL
Position of mature hormone in Pre-Hormone protein62 Residues from position (27-88)
ReceptorN/A
Gene ID692740      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated